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Chen, Zan M.D., Ph.D.

Chen, Zan   M.D., Ph.D.

Professor of Neurosurgery

Senior Consultant Neurosurgeon

Neurospine Center

Clinical Expertise:



Cranial vertebral junction malformation surgery, Cervical spine surgery, Spine and spine canal tumor surgery, Lumbar spine minimal invasive surgery

Research Interests

The biomechanism of CVJ malformation; the genetics of spinal chordoma


Dr. Chen received his B.S. and M.D. from the Harbin Medical University in 1999. He completed his residency in neurological surgery at the 2nd Hospital affiliated to Harbin Medical University and Xuanwu Hospital in 2006, he focused on neuro-spine surgery since then, especially cervical spine surgery. He has accumulated much experience on complex cervical spine disorders, including CVJ malformation, cervical spine tumors, and cervical OPLL.


MD PhD, Harbin Medical University (1999)


Harbin Medical University (2001)


Harbin Medical University and Capital Medical University (2006)

Professional Memberships

1. Member of spine committee, World Federation of Neurological Surgery (WFNS)

2. Executive committee member of Craniovertebral Junction & Spine Society

3. Vice president of the spine and spinal cord committee of the Chinese Congress of Neurosurgery (affiliated to the Chinese Medical Association)

4. Executive committee member of Chinese Association of Neurological Surgeons (affiliated to the Chinese Medical Doctor Association)

5. AOspine Faculty

Research & Publications 

1. Guan J, Chen Z, Wu H, et al. Effectiveness of posterior reduction and fixation in atlantoaxial dislocation: a  retrospective cohort study of 135 patients with a treatment algorithm proposal[J]. EUR SPINE J, 2019,28(5):1053-1063.DOI:10.1007/s00586-018-05869-z

2. Liu Z, Duan W, Wu H, et al. Quantitative Correction of Cervical Sagittal Deformity in Atlanto-Axial Dislocation[J]. Spine (Phila Pa 1976), 2019,44(14):975-981.DOI:10.1097/BRS.0000000000002999

3. Wang K, Zhang C, Wu H, et al. The Anatomic Characteristics of the Retroperitoneal Oblique Corridor to the L1-S1 Intervertebral Disc Spaces[J]. Spine (Phila Pa 1976), 2019,44(12):E697-E706.DOI:10.1097/BRS.0000000000002951

4. Lu F, Chen Z, Wu H, et al. Magnetic Resonance Imaging of Chiari Malformation Type I in Adult Patients with Dysphagia[J]. BIOMED RES INT, 2019,2019:7485010.DOI:10.1155/2019/7485010

5. Duan W, Du Y, Qi T, et al. The Value and Limitation of Cervical Traction in the Evaluation of the Reducibility of Atlantoaxial Dislocation and Basilar Invagination Using the Intraoperative O-Arm[J]. WORLD NEUROSURG, 2019,132:e324-e332.DOI:10.1016/j.wneu.2019.08.160

6. Du YQ, Duan W R, Chen Z, et al. Carotid Artery-Related Perioperative Stroke Following Anterior Cervical Spine Surgery: A Series of 3 Cases and Literature Review[J]. J Stroke Cerebrovasc Dis, 2019,28(2):458-463.DOI:10.1016/j.jstrokecerebrovasdis.2018.10.024

7. Duan W, Chou D, Jiang B, et al. Posterior revision surgery using an intraarticular distraction technique with cage grafting to treat atlantoaxial dislocation associated with basilar invagination[J]. J Neurosurg Spine, 2019:1-9.DOI:10.3171/2019.4.SPINE1921

8. Du YQ, Duan W R, Chen Z, et al. Predictors for Development of Symptomatic Myelopathy in Patients with Radiculopathy Caused by Cervical Ossification of Posterior Longitudinal Ligament[J]. WORLD NEUROSURG, 2019.DOI:10.1016/j.wneu.2018.12.199

9. Xie Q, Zhang J, Lu F, et al. Minimally invasive versus open Transforaminal lumbar Interbody fusion in obese patients: a meta-analysis[J]. BMC Musculoskelet Disord, 2018,19(1):15.DOI:10.1186/s12891-018-1937-6

10. Du YQ, Duan W R, Chen Z, et al. Risk Factors and Management of Dural Defects in Anterior Surgery for Cervical Ossification of the Posterior Longitudinal Ligament[J]. WORLD NEUROSURG, 2018,111:e527-e538.DOI:10.1016/j.wneu.2017.12.113

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