Research Interest

Stroke; Cerebral venous sinus thrombosis; Remote ischemic preconditioning; Intravascular hypothermia

Background

Prof. Xun-ming Ji (MD, PhD), as a Chief Physician and Doctorial Tutor in neurosurgery, is the Vice-president of Capital Medical University and the President of Beijing Institute for Brain Disorders. He has been elected as the ‘China National Funds for Distinguished Youth Scientist’, the ‘Distinguished Professor of Cheung Kong Scholars Program’ and State Council Expert for Special Allowance.

Prof. Ji engages in the research of stroke screening and prevention, including the thrombolysis for acute cerebral infarction, neuroprotective therapy, chronic cerebral ischemia of adaptive protection treatment and the diagnosis and treatment of cerebral venous disease. He has published more than 500 papers and one book - “Endovascular Intervention for Acute Stroke”. He received seven Provincial-level scientific and technological progress awards, including the Second prize of China's State Natural Science Award, First Prize of Medical Science of Chinese Medical Association, First Prize of Science and Technology Progress Award of Ministry of Education. 

Education

1986.09 - 1991.08    Nantong Medical College. Bachelor

1995.09 - 1998.07    Tianjin Medical University. Master

1998.10 - 2000.07    Tianjin Medical University. PhD

2007.08 - 2009.08    China-Europe International Business School. MBA

Awards & Honors

1. Beijing Nova program of Science and Technology

2. Backbone talents of Beijing Organization Department

3. The persons of Beijing New Century National Hundred, Thousand and Ten Thousand Talent Project

4. Talents of the education ministry in the new century

5. Backbone talents of Beijing Sanitation System

6. National Outstanding Director of science popularization

7. China National Funds for Distinguished Youth Scientists

8. Distinguished Professor of cheung kong scholars programme

9. Leading talents of Youth Science and technology innovation

Professional Memberships

1. American Association of Conditioning Medicine. President

2. International Conditioning Medical Association. President

3. Cerebrovascular disease of Chinese Association for the elderly. President

4. Cerebral venous disease of Chinese Stroke Association. Director

5. Chinese Association for the elderly. Vice president

6. Chinese stroke association executive director of the first session of the council

7. International Aging and Disease Association. Vice President

8. Beijing brain major disease research institute. Director

9. Sino-us joint research institute in neuroscience. Director of Chinese Side

10. International Association of Stroke. Member

11. Stroke screening and Prevention Engineering Committee for National Health and Family Planning Commission the People's Republic of China. Deputy Director of the Committee

12. Diagnosis and Treatment center of High Cranial Pressure and cerebral venous disease for the Ministry of Health. Director

13. International Society of Cerebral Blood Flow and Metabolism. Member

14. Geriatric medicine professional committee of Geriatric Society of China. Deputy Director of the Committee

15. Beijing Municipal Science and Technology Commission. Chief Expert of Cerebrovascular Disease Research

16. American Stroke Association. Member

Research & Publications

1. Transfer of mitochondria from astrocytes to neurons after stroke. Kazuhide Hayakawa, Elga Esposito, Xiaohua Wang, Yasukazu Terasaki, Yi Liu, Changhong Xing, Xunming Ji (Corresponding Author) , Eng H. Lo (Corresponding Author). Nature. 2016, 535(7613): 551-555

2. Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury. Yejie Shi, Lili Zhang, Hongjian Pu, Leilei Mao, Xiaoming Hu, Xiaoyan Jiang, Na Xu, R. Anne Stetler, Feng Zhang, Xiangrong Liu, Rehana K. Leak, Richard F. Keep, Xunming Ji(Corresponding Author), Jun Chen(corresponding author). Nature Communications, 2016, 7: 10523.

3. Safety and Efficacy of Remote Ischemic Preconditioning in Patients with Severe Carotid Artery Stenosis Prior to Carotid Artery Stenting: A Proof-of-Concept, Randomized Controlled Trial. Wenbo Zhao, Ran Meng, Chun Ma, Baojun Hou, Liqun Jiao, Fengshui Zhu, Weijuan Wu, Jingfei Shi, Yunxia Duan, Renling Zhang, Jing Zhang, Yongxin Sun, Hongqi Zhang, Feng Ling, Yuping Wang, Wuwei Feng, Yuchuan Ding, Bruce Ovbiagele, and Xunming Ji (Corresponding Author). Circulation, 2017, 135(14): 1325- 1335.

4. Elevated trimethylamine N-oxide related to ischemic brain lesions after carotid artery stenting. Chuanjie Wu, Chuanhui Li, Wenbo Zhao, Nanchang Xie, Feng Yan, Yajun Lian, Li Zhou, Xiaoya Xu, Yong Liang, Lu Wang, Ming Ren, Sijie Li, Xuan Cheng, Lu Zhang, Qingfeng Ma, Haiqing Song, Ran Meng, Xunming Ji (Corresponding Author). Neurology. 2018, 90(15): e1283-e1290.

5. Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Ran Meng, Karam Asmaro, Lu Meng, Yu Liu, Chun Ma, Chunjiang Xi, Guoqing Li, Canghong Ren, Yumin Luo, Feng Ling, Jianping Jia, Yang Hua, Xiaoying Wang, Yuchuan Ding, Eng H. Lo, Xunming Ji (Corresponding Author). Neurology. 2012, 79(18): 1853-1861.

6. Endovascular Hypothermia in Acute Ischemic Stroke: Pilot Study of Selective Intra-Arterial Cold Saline Infusion. Jian Chen, Liqiang Liu, Hongqi Zhang, Xiaokun Geng, Liqun Jiao, Guilin Li, Jonathan M. Coutinho, Yuchuan Ding, David S. Liebeskind, Xunming Ji (Corresponding Author). Stroke. 2016, 47(7): 1933-1935. 

7. Remote Ischemic Conditioning May Improve Outcomes of Patients With Cerebral Small-Vessel Disease. Yuan Wang, Ran Meng, Haiqing Song, Gang Liu, Yang Hua, Dehua Cui, Lemin Zheng, Wuwei Feng, David S. Liebeskind, Marc Fisher, Xunming Ji (Corresponding Author). Stroke. 2017, 48(11):3064-3072.

8. Early Detection and Quantification of Cerebral Venous Thrombosis by Magnetic Resonance Black-Blood Thrombus Imaging. Qi Yang, Jiangang Duan, Zhaoyang Fan, Xiaofeng Qu, Yibin Xie, Christopher Nguyen, Xiangying Du, Xiaoming Bi, Kuncheng Li (Corresponding Author), Xunming Ji (Corresponding Author), Debiao Li. Stroke, 2016, 47(2): 404-409.

9. Safety, feasibility, and potential efficacy of intraarterial selective cooling infusion for stroke patients treated with mechanical thrombectomy. Chuanjie Wu, Wenbo Zhao, Hong An, Longfei Wu, Jian Chen, Mohammed Hussain, Yuchuan Ding, Chuanhui Li, Wenjing Wei, Jiangang Duan, Chunmei Wang, Qi Yang, Di Wu, Liqiang Liu, Xunming Ji (Corresponding Author). Journal of Cerebral Blood Flow & Metabolism. 2018, 38(12): 2251-2260.

10. Safety and validity of mechanical thrombectomy and thrombolysis on severe cerebral venous sinus thrombosis. Guangwen Li, Xianwei Zeng, Mohammed Hussain, Ran Meng,  Yi Liu,  Kevin Yuan, Chaitanya Sikharam, Yuchuan Ding, Feng Ling, Xunming Ji (Corresponding Author). Neurosurgery, 2013, 72(5): 730-738.